Tsubasa Watanabe Selected Research

Neoplasms (Cancer)

5/2022	The mutual relationship between the host immune system and radiotherapy: stimulating the action of immune cells by irradiation.
1/2022	Boron neutron capture therapy using dodecaborated albumin conjugates with maleimide is effective in a rat glioma model.
12/2021	Efficacy of Boron Neutron Capture Therapy in Primary Central Nervous System Lymphoma: In Vitro and In Vivo Evaluation.
1/2021	HIF-1α affects sensitivity of murine squamous cell carcinoma to boron neutron capture therapy with BPA.
12/2020	The Therapeutic Effects of Dodecaborate Containing Boronophenylalanine for Boron Neutron Capture Therapy in a Rat Brain Tumor Model.
9/2020	Deep abscopal response to radiotherapy and anti-PD-1 in an oligometastatic melanoma patient with unfavorable pretreatment immune signature.
1/2020	Adding Indoximod to Hypofractionated Radiotherapy with Anti-PD-1 Checkpoint Blockade Enhances Early NK and CD8+ T-Cell-Dependent Tumor Activity.
12/2019	Cisplatin Facilitates Radiation-Induced Abscopal Effects in Conjunction with PD-1 Checkpoint Blockade Through CXCR3/CXCL10-Mediated T-cell Recruitment.
1/2019	Proposal for determining absolute biological effectiveness of boron neutron capture therapy-the effect of 10B(n,α)7Li dose can be predicted from the nucleocytoplasmic ratio or the cell size.
3/2018	Impact of oxygen status on 10B-BPA uptake into human glioblastoma cells, referring to significance in boron neutron capture therapy.

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Tsubasa Watanabe Research Topics

Disease

18	Neoplasms (Cancer) 05/2022 - 12/2010
4	Infections 06/2022 - 01/2017
4	Hypoxia (Hypoxemia) 01/2021 - 07/2014
4	Neoplasm Metastasis (Metastasis) 09/2020 - 07/2014
4	Melanoma (Melanoma, Malignant) 09/2020 - 07/2014
3	Brain Neoplasms (Brain Tumor) 01/2022 - 03/2016
3	Hyperthermia 10/2017 - 07/2014
2	Glioma (Gliomas) 01/2022 - 12/2020
2	Lymphoma (Lymphomas) 12/2021 - 01/2021
1	Squamous Cell Carcinoma (Epidermoid Carcinoma) 01/2021
1	Lymphopenia (Lymphocytopenia) 12/2019
1	Glioblastoma (Glioblastoma Multiforme) 03/2018
1	Collagen Diseases (Collagen Disease) 01/2017
1	Gastrointestinal Diseases (Functional Gastrointestinal Disorders) 01/2017
1	Amyloidosis 01/2017
1	Rheumatoid Arthritis 01/2017
1	Necrosis 12/2015
1	Carcinoma (Carcinomatosis) 01/2015
1	Neurocognitive Disorders (Clerambault Syndrome) 03/2014
1	Mitochondrial Diseases (Mitochondrial Disease) 04/2013
1	Heart Diseases (Heart Disease) 04/2013
1	Desmoplastic Small Round Cell Tumor 01/2012
1	Pancreatitis 10/2011
1	Leukemia 12/2010

Drug/Important Bio-Agent (IBA)

6	BoronIBA 01/2022 - 03/2016
4	Bromodeoxyuridine (BrdU)IBA 10/2017 - 01/2014
2	Biological ProductsIBA 01/2022 - 12/2010
2	Methotrexate (Mexate)FDA LinkGeneric 12/2021 - 01/2017
2	Phenylalanine (L-Phenylalanine)FDA Link 12/2021 - 01/2019
2	Immune Checkpoint InhibitorsIBA 09/2020 - 12/2019
2	Proteins (Proteins, Gene)FDA Link 03/2018 - 01/2015
2	psymberinIBA 01/2015 - 12/2010
2	Niacinamide (Nicotinamide)FDA LinkGeneric 08/2014 - 07/2014
2	SodiumIBA 07/2014 - 01/2014
1	Anti-Bacterial Agents (Antibiotics)IBA 06/2022
1	Neoplasm Antigens (Tumor Antigens)IBA 05/2022
1	AntigensIBA 05/2022
1	AlbuminsIBA 01/2022
1	maleimideIBA 01/2022
1	Colistin (Coly-Mycin)FDA Link 03/2021
1	Adrenal Cortex Hormones (Corticosteroids)IBA 01/2021
1	SuspensionsIBA 01/2021
1	Large Neutral Amino Acid-Transporter 1IBA 01/2021
1	AmidesIBA 12/2020
1	Therapeutic UsesIBA 12/2020
1	dodecaborateIBA 12/2020
1	Differentiation AntigensIBA 09/2020
1	ChemokinesIBA 09/2020
1	1-methyltryptophanIBA 01/2020
1	Antineoplastic Agents (Antineoplastics)IBA 12/2019
1	Cisplatin (Platino)FDA LinkGeneric 12/2019
1	Messenger RNA (mRNA)IBA 03/2018
1	Amino Acid Transport Systems (Amino Acid Transporter)IBA 03/2018
1	Oxygen (Dioxygen)IBA 03/2018
1	Tirapazamine (SR 4233)IBA 10/2017
1	pimonidazoleIBA 10/2017
1	Metformin (Glucophage)FDA LinkGeneric 10/2017
1	Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA 01/2017
1	SteroidsIBA 01/2017
1	Prednisolone (Predate)FDA LinkGeneric 01/2017
1	HeliumIBA 12/2015
1	Protons (Proton)IBA 12/2015
1	Tumor Necrosis Factor Receptors (Tumor Necrosis Factor Receptor)IBA 01/2015
1	Phosphotransferases (Kinase)IBA 01/2015
1	JNK Mitogen-Activated Protein KinasesIBA 01/2015
1	Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)IBA 01/2015
1	MitogensIBA 01/2015
1	Thalidomide (Thalomid)FDA Link 08/2014
1	Bevacizumab (Avastin)FDA Link 07/2014
1	4-boronophenylalanineIBA 07/2014
1	antineoplaston A10 (A 10)IBA 01/2014
1	Multidrug Resistance-Associated ProteinsIBA 04/2013
1	Member 1 Subfamily B ATP Binding Cassette TransporterIBA 04/2013
1	Angiopoietin-2IBA 10/2011
1	Protein Kinases (Protein Kinase)IBA 12/2010
1	pederinIBA 12/2010

Therapy/Procedure

9	Boron Neutron Capture Therapy 01/2022 - 07/2014
8	Radiotherapy 12/2021 - 12/2015
6	Therapeutics 03/2021 - 01/2012
1	Re-Irradiation 01/2020
1	Drug Therapy (Chemotherapy) 03/2018
1	Catheters 01/2017
1	Aftercare (After-Treatment) 03/2014